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C19H19N3O6

Nilvadipine is a calcium channel blocker used for the treatment of hypertension and chronic major cerebral artery occlusion. Pathohistochemical studies have revealed that the volume of the infarction in the middle cerebral artery occlusion model ...

C20H19N3O4S

Rivoglitazone is a thiazolidinedione derivative undergoing research for use in the treatment of type 2 diabetes. It is being developed by Daiichi Sankyo.

C28H39N3O2

SNC-80 is an opioid analgesic drug that selectively activates μ–δ opioid receptor heteromers and is used in scientific research. It was discovered in 1994. SNC-80 was the first non-peptide drug developed that was regarded as a highly selective ag ...

C21H32O5S

Pregnenolone sulfate is an endogenous excitatory neurosteroid that is synthesized from pregnenolone. It is known to have cognitive and memory-enhancing, antidepressant, anxiogenic, and proconvulsant effects.

C23H36N6O5S

Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. In 2000, argatroban was licensed by the Food and Drug Administration for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia. ...

C24H29NO2

F-15.063 is an orally active potential antipsychotic, and an antagonist at the D 2 /D 3 receptors, partial agonist at the D 4 receptor, and agonist at the 5-HT 1A receptors. It has greater efficacy at the 5-HT 1A receptors than other antipsychoti ...

C23H26N4O5

HZ-2 is a drug which acts as a highly selective κ-opioid agonist. It is a potent analgesic with around the same potency as morphine, with a long duration of action and high oral bioavailability. Side effects include sedation, nausea and dysphoria ...

C21H19N5O7

Farinamycin is a quinazoline metabolite that has been isolated from Streptomyces griseus. It is the first known metabolite to be produced by S. griseus that is not a phenoxazinone antibiotic. Farinamycin is formed from the condensation of 3-OH-an ...

C22H32Cl2N2O4

Lorglumide is a drug which inhibits gastrointestinal motility and reduces gastric secretions, acting as a cholecystokinin antagonist, with fairly high selectivity for the CCK A subtype. It has been suggested as a potential treatment for a variety ...

C23H40N2O4

Capsinolol is a beta blocker derived from nonivamide. It is the first beta blocker with an associated calcitonin gene-related peptide releasing activity in the heart.

C22H32O

JWH-133 is a potent selective CB 2 receptor agonist with a Ki of 3.4nM and selectivity of around 200x for CB 2 over CB 1 receptors. It was discovered by and named after, John W. Huffman. JWH-133, alongside WIN 55.212-2 and HU-210, is responsible ...

C28H41N2P

CPhos is a phosphine ligand derived from biphenyl. It is a white solid that is soluble in organic solvents. Its palladium complexes exhibit high activity for Negishi coupling reactions involving aryl bromides, chlorides and triflates. CPhos media ...

C20H20N4

Hexahydroporphine is an organic chemical compound with formula C 20 H 20 N 4. The molecule consists of four pyrrole rings connected by methylene bridges −CH 2 − into a larger macrocycle ring, which makes it one of the simplest tetrapyrroles, and ...

C22H34O5

Pleuromutilin and its derivatives are antibacterial drugs that inhibit protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes. This class of antibiotics includes the licensed drugs lefamulin ...

C27H30N4O4

Darexaban is a direct inhibitor of factor Xa created by Astellas Pharma. It is an experimental drug that acts as an anticoagulant and antithrombotic to prevent venous thromboembolism after a major orthopaedic surgery, stroke in patients with atri ...

C28H43NO6

Borrelidin is an 18-membered polyketide macrolide derived from several Streptomyces species. First discovered in 1949 from Streptomyces rochei, Borrelidin shows antibacterial activity by acting as an inhibitor of threonyl-tRNA synthetase and feat ...

C19H19NS

Pimethixene is an antihistamine and anticholinergic of the thioxanthene chemical class that is often used to treat hyperactivity, anxiety, sleep disorders, and allergy. It is also used for anesthesia and as a bronchodilator.

C19H20BrN3O3

Bretazenil is an imidazopyrrolobenzodiazepine anxiolytic drug which is derived from the benzodiazepine family, and was invented in 1988. It is most closely related in structure to the GABA antagonist flumazenil, although its effects are somewhat ...

C22H35NO3

N -Arachidonylglycine NAGly is a carboxylic metabolite of the endocannabinoid anandamide AEA. Since it was first synthesized in 1996, NAGly has been a primary focus of the relatively contemporary field of lipidomics due to its wide range of signa ...

C19H20BrNO2

6-Br-APB is a synthetic compound that acts as a selective D 1 agonist, with the -enantiomer being a potent full agonist, while the enantiomer retains its D 1 selectivity but is a weak partial agonist. -6-Br-APB and similar D 1 -selective full ago ...

C20H20N6O7S4

Cefodizime is a 3rd generation cephalosporin antibiotic with broad spectrum activity against aerobic gram positive and gram negative bacteria. Clinically, it has been shown to be effective against upper and lower respiratory tract infections, uri ...

C19H20ClN3

Benzimidazoles substituted with an alkylamine at position 2 have a venerable history as H 1 antihistaminic agents. The standard starting material for many benzimidazoles consists of phenylenediamine, or its derivatives. Reaction of that compound ...

C20H20O4

Glabridin is a chemical compound that is found in the root extract of licorice. Glabridin is an isoflavane, a type of isoflavonoid. This product is part of a larger family of plant-derived molecules, the natural phenols. It is used as an ingredie ...

C19H20ClN3O4S

W-18 is a compound in a series of 32 substances that were first synthesized in academic research on analgesic drug discovery in the 1980s and appeared as a designer drug in the 2010s. W-18 was invented at the University of Alberta by a lab workin ...

C27H31I2NO5

Budiodarone is an antiarrhythmic agent and chemical analog of amiodarone that is currently being studied in clinical trials. Amiodarone is considered the most effective antiarrhythmic drug available, but its adverse side effects, including hepati ...

C27H31NO

1-Benzyl-4- ​ethyl) ​piperidine is a stimulant of the piperidine class which acts as a potent and selective dopamine reuptake inhibitor. It is closely related to vanoxerine and GBR-12.935, which in contrast are piperazines.

C31H24O3

Difenacoum is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It has anticoagulant effects and is used commercially as a rodenticide. It was first introduced in 1976 and first registered in the USA in 2007.

C26H33NO6

Lacidipine is a calcium channel blocker. It is available as tablets containing 2 or 4 mg. It was patented in 1984 and approved for medical use in 1991.

C22H25Cl2N3O3

Brilaroxazine, also known by the developmental code names RP-5063 and RP-5000, is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. Revi ...

C28H46O9

Butyrolactol A is an organic chemical compound of interest for its potential use as an antifungal antibiotic. One of a number of potentially useful substances derived from the bacteria Streptomyces rochei, it demonstrates broad antimicrobial acti ...

C22H25F2N3O

A-423.579 is one of a range of histamine antagonists developed by Abbott Laboratories which are selective for the H 3 subtype, and have stimulant and anorectic effects in animal studies making them potentially useful treatments for obesity. A-423 ...

C31H33N3O11

Azinomycin B is a natural product that contains densely assembled functionalities with potent antitumor activity. It is isolated from Streptomyces sahachiroi which is reisolated from S. griseofuscus along with its analog azinomycin A. Azinomycin ...

C28H26N2O10

Balanol is a fungal metabolite produced by the fungus Verticillium balanoides. It is a potent inhibitor of the serine/threonine kinases protein kinase A and protein kinase C, binding in a similar manner with that of ATP. Balanol was discovered in ...

C19H20FN5O4

Zabofloxacin is an investigational fluoroquinolone antibiotic for multidrug-resistant infections due to Gram-positive bacteria. It also has activity against Neisseria gonorrhoeae including strains that are resistant to other quinolone antibiotics ...

C21H26O4

Canniprene is an isoprenylated bibenzyl found in the fan leaves of Cannabis sativa. Canniprene can be vaporized and therefore potentially inhaled from cannabis.

C26H34O6

Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans. It has similar effects to digitalis and is used in traditional Chinese medicine.

C28H27Cl2N3O7S

Relcovaptan is a non-peptide vasopressin receptor antagonist, selective for the V1a subtype. It has shown positive initial results for the treatment of Raynauds disease and dysmenorrhoea, and as a tocolytic, although it is not yet approved for cl ...

C24H30O5

Beraprost is a pharmaceutical drug used in several Asian countries, including Japan and South Korea, as a vasodilator and antiplatelet agent. It is classified as a prostacyclin analog. It has been studied for the treatment of pulmonary hypertensi ...

C28H58O

1-Octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol that is common in the epicuticular waxes of plants, including the leaves of many species of Eucalyptus, of most forage and cereal grasses, of Acacia, Trifolium, Pisum and ...

C26H25N3O2

JTC-801 is an opioid analgesic drug used in scientific research. JTC-801 is a selective antagonist for the nociceptin receptor, also known as the ORL-1 receptor. This was the fourth opioid receptor to be discovered and is still the least understo ...

C22H25N3O2S

S-14671 is a naphthylpiperazine derivative which acts as a 5-HT 1A receptor agonist with high efficacy and exceptional in vivo potency, and also as a 5-HT 2A and 5-HT 2C receptor antagonist. It displays only low and non-significant affinity for 5 ...

C24H30O11

Harpagoside is a natural product found in the plant Harpagophytum procumbens, also known as devils claw. It is the active chemical constituent responsible for the medicinal properties of the plant, which have been used for centuries by the Khoisa ...

C19H20N2

Mebhydrolin or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal and Diazolin. It is used for symptomatic relief of allergic symptoms caused by histamine ...

C31H38FN3O

DPI-221 is an opioid drug that is used in scientific research. It is a highly selective agonist for the δ-opioid receptor, which produces fewer convulsions than most drugs from this family.

C29H20O

Tetraphenylcyclopentadienone is an organic compound with the formula 4 C 4 CO. It is a dark purple to black crystalline solid that is soluble in organic solvents. It is an easily made building block for many organic and organometallic compounds.

C22H25NO4

Pitofenone is an antispasmodic. Pitofenone is typically used in combination with fenpiverinium bromide, and metamizole sodium. Previously produced as Baralgin by Sanofi Aventis, the drug is currently sold in Eastern Europe under various trade nam ...

C24H12

Coronene is a polycyclic aromatic hydrocarbon comprising six peri-fused benzene rings. Its chemical formula is C 24 H 12. It is a yellow material that dissolves in common solvents including benzene, toluene, and dichloromethane. Its solutions emi ...

C31H38N2O3

Codinaeopsin is an antimalarial isolated from a fungal isolate found in white yemeri trees in Costa Rica. It is reported to have bioactivity against Plasmodium falciparum with an IC 50 = 2.3 μg/mL. Pure codinaeopsin was reported to be isolated wi ...

C32H64O4Sn

Dibutyltin dilaurate, also called dibutyltindilaurate or butynorate, is an organotin compound that is used as a catalyst. It is a colourless oily liquid. In terms of its structure, the molecule consists of two laurate groups attached to a dibutyl ...

C31H38N2O3S3

RB-101 is a drug that acts as an enkephalinase inhibitor, which is used in scientific research. RB-101 is a prodrug which acts by splitting at the disulfide bond once inside the brain, to form two selective enzyme inhibitors and blocking both typ ...